RecruitingNot ApplicableNCT06284174

Effectiveness of Povidone-Iodine Versus Chlorhexidine Gluconate Solutions in Reducing Microbial Contamination in Spinal Surgery Wounds During Intraoperative Soaking.


Sponsor

National Cheng-Kung University Hospital

Enrollment

105 participants

Start Date

Jan 1, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to assess the efficacy of intraoperative wound irrigation with iodine-containing and chlorhexidine-containing solutions in reducing bacterial colonization during spine surgery, and to determine which solution is more effective. Additionally, we aim to evaluate any side effects associated with the use of these two antiseptic solutions for wound irrigation.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Patients who were diagnosed with lumbar spinal stenosis need to undergo posterior lumbar decompression with fusion surgery.

Exclusion Criteria3

  • People who are allergic to disinfectants (Providine or CHG)
  • The surgical site has been operated before.
  • Patients under active infection status.

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Interventions

DRUGPovidone-iodine solution; chlorhexidine gluconate

Before wound closure, each group will undergo different irrigation solutions for soaking the wound for three minutes followed by rinsing with copious saline.


Locations(1)

National Cheng Kung University Hospital

Tainan, Taiwan, Taiwan

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NCT06284174