RecruitingNCT06287671

Colorectal Omics and OfCS Proteoglycans

Colorectal OmiCs and Oncofetal Chondroitin Sulfate-modified Proteoglycans


Sponsor

Claus Anders Bertelsen, PhD, MD

Enrollment

1,000 participants

Start Date

Oct 8, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This observational study aims to test proteomics, metabolomics and proteoglycans as predictors of postoperative complications after colorectal surgery and as biomarkers of colorectal cancer. The main questions to answer are: * can these biomarkers predict anastomotic leakages * can these biomarkers predict recurrence after colorectal cancer * can these biomarkers be used as diagnostic tests for colorectal cancer * can these biomarkers be identified in the tumor Participants will undergo elective colorectal resection or stoma closure.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is collecting tissue and blood samples from patients undergoing colorectal surgery to study specific proteins and molecular markers that may help better understand colorectal cancer, inflammatory bowel disease, and other colon conditions. **You may be eligible if...** - You have been diagnosed with or are suspected to have colorectal cancer, colorectal polyps, inflammatory bowel disease, or another condition requiring colorectal surgery - You are scheduled for a planned (elective) colorectal surgery procedure - You are able to provide informed consent and can communicate in Danish, English, or another language with available professional interpretation **You may NOT be eligible if...** - You are having simultaneous liver, stomach, or major pancreatic surgery along with your colorectal procedure - You are unable or unwilling to provide consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREColorectal resection or stoma closure

Elective open or minimally invasive resection for colorectal cancer, IBD or other benign colorectal disorder, or stoma closure


Locations(2)

Nordsjaellands Hospital

Hillerød, Denmark

Regionshospitalet Viborg

Viborg, Denmark

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NCT06287671


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