RecruitingNCT06291805

Phenotyping and Characterization of wtATTR-CM (TRACE 1)

Phenotyping and Characterization of Danish Wild-type Transthyretin Amyloidosis Cardiomyopathy Patients: A Cross-sectional Study

Sponsor

Steen Hvitfeldt Poulsen

Enrollment

120 participants

Start Date

Feb 20, 2024

Study Type

OBSERVATIONAL

Conditions

Quality of Life Transthyretin Amyloid Cardiomyopathy Transthyretin Amyloidosis Wild-Type Transthyretin-Related (ATTR)Amyloidosis

Summary

Descriptive cross-sectional study on 100 consecutive ATTRwt-CM patients reflecting all NAC stages aiming primarily to investigate ATTRwt-CM patient's quality of life (QoL) measures and their relation to ATTRwt-CM severity. Secondarily aiming to investigate the possibility to measure misTTR and fragTTR in plasma and urine and to detect fragTTR in endomyocardial biopsies from ATTRwt-CM patients. To investigate whether misTTR and fragTTR levels are correlated with ATTRwt-CM severity.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with quality of life, transthyretin amyloid cardiomyopathy, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Aarhus University Hospital

Aarhus, Arrhus N, Denmark

View Full Details on ClinicalTrials.gov

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NCT06291805

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