RecruitingNot ApplicableNCT06295744

Outcomes and Cosmesis With Whole Breast Irradiation and Boost

Patient-Reported Outcomes and Cosmesis Following Five Fraction Whole Breast Irradiation With Simultaneous Integrated Boost


Sponsor

University of Wisconsin, Madison

Enrollment

50 participants

Start Date

Apr 17, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study is being done to evaluate cosmetic, patient-reported outcome measures (PROMs), and toxicities for women undergoing ultra-short whole breast irradiation (WBI) therapy with simultaneous integrated boost (SIB). 50 participants will be on study for up to 60 months.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study looks at long-term outcomes and cosmetic results for women with early-stage breast cancer who have a lumpectomy (breast-conserving surgery) followed by whole breast radiation therapy plus a targeted radiation boost to the tumor area. **You may be eligible if...** - You have been diagnosed with early-stage invasive breast cancer (Stage T1 or T2) or DCIS (a non-invasive form of breast cancer) - You had a lumpectomy with clear margins and no cancer in the lymph nodes - Your treatment plan includes whole breast radiation followed by a tumor bed boost - You are willing and able to attend follow-up visits **You may NOT be eligible if...** - You had a full mastectomy (breast removal) - Your cancer has spread to the lymph nodes or other parts of the body - You have had previous breast cancer on the same side or previous chest radiation - You have an active connective tissue disease such as scleroderma - You are receiving chemotherapy at the same time as radiation - You have had another cancer (other than minor skin cancers) in the past 5 years Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONRadiation Therapy

WBI with SIB delivered over 5 fractions


Locations(1)

UW Carbone Cancer Center

Madison, Wisconsin, United States

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NCT06295744


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