RecruitingNot ApplicableNCT06296186

Massed Prolonged Exposure for PTSD in Substance Use Treatment

Clinical Effectiveness and Implementation of Massed Prolonged Exposure for PTSD Among Veterans in Intensive Outpatient Substance Use Treatment (MPE)

Sponsor

Veterans Medical Research Foundation

Enrollment

200 participants

Start Date

Sep 1, 2024

Study Type

INTERVENTIONAL

Conditions

Stress Disorders, Post-Traumatic Substance Use Disorders

Summary

The goal of this clinical trial is to learn if receiving Prolonged Exposure Therapy for PTSD in massed format (multiple sessions weekly) is as effective as receiving it with sessions once per week among veterans with PTSD and substance use disorder in intensive outpatient substance use treatment. The main questions it aims to answer are: * Will the massed format help participants complete and benefit from Prolonged Exposure in terms of PTSD symptoms? * Will it help participants reduce substance use? Participants who are in intensive substance use treatment will be asked to complete Prolonged Exposure with either weekly sessions or multiple sessions per week.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests a form of intensive, condensed PTSD therapy called Massed Prolonged Exposure — where multiple therapy sessions are delivered over a short period — for veterans who are also dealing with a substance use problem. **You may be eligible if...** - You are a veteran aged 18 or older who served after September 2001 - You are currently enrolled in an intensive outpatient substance use program at a VA facility - You have been diagnosed with both PTSD and a substance use disorder - You have used substances on at least 20 of the past 90 days **You may NOT be eligible if...** - You have severe cognitive impairment - You have current thoughts of harming yourself or others that require immediate treatment - You have unstable psychotic symptoms or mania that are not related to substance use Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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