RecruitingPhase 4NCT06296836

Effect of Continuing Versus Holding Metformin During Hospitalizations.

Effect of Continuing Versus Holding Metformin During Hospitalizations to Internal Medicine on Glucose Control, Acidosis, Abdominal Symptoms, Length of Stay, and Mortality.

Sponsor

University of Illinois at Chicago

Enrollment

300 participants

Start Date

Jan 21, 2025

Study Type

INTERVENTIONAL

Conditions

Diabetes Mellitus, Type 2

Summary

A randomized study of continuing versus holding metformin during hospitalizations to internal medicine services to determine the effects on glucose control, acidosis, abdominal symptoms, length of stay, and mortality.

Eligibility

Min Age: 18 YearsMax Age: 110 Years

Plain Language Summary

Simplified for easier understanding

This study looks at whether it is safe and beneficial to continue taking metformin (a common diabetes pill) while a person is in the hospital, or whether it should be paused during admission as is often done. **You may be eligible if...** - You are 18 or older - You were admitted to a general medicine ward - You were taking metformin before your hospital admission **You may NOT be eligible if...** - You cannot swallow oral medications - Your kidney function is significantly reduced (eGFR below 30) - You are on dialysis - You currently have acidosis (low blood pH) including diabetic ketoacidosis - You have severe liver disease (Child-Turcotte-Pugh class C) - You have acute decompensated heart failure - You have cognitive impairment or cannot give consent - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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