Diabetes Mellitus, Type 2 Clinical Trials

226 recruitingLast updated: June 17, 2026

There are 226 actively recruiting diabetes mellitus, type 2 clinical trials across 60 countries. Studies span Not Applicable, Phase 4, Phase 1, Phase 2, Phase 3, Early Phase 1. Top locations include Seoul, South Korea, Boston, Massachusetts, United States, Montreal, Quebec, Canada. Updated daily from ClinicalTrials.gov.


Diabetes Mellitus, Type 2 Trials at a Glance

226 actively recruiting trials for diabetes mellitus, type 2 are listed on ClinicalTrialsFinder across 6 cities in 60 countries. The largest study group is Not Applicable with 127 trials, with the heaviest enrollment activity in Seoul, Boston, and Montreal. Lead sponsors running diabetes mellitus, type 2 studies include Eli Lilly and Company, Novo Nordisk A/S, and Stanford University.

Browse diabetes mellitus, type 2 trials by phase

Treatments under study

About Diabetes Mellitus, Type 2 Clinical Trials

Looking for clinical trials for Diabetes Mellitus, Type 2? There are currently 225 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Diabetes Mellitus, Type 2 trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Diabetes Mellitus, Type 2 clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 226 trials

Recruiting
Not Applicable

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

Metabolic SyndromeDiabetes Mellitus, Type 2Prediabetes
Cleerly, Inc.7,500 enrolled124 locationsNCT06112418
Recruiting
Not Applicable

Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery

Diabetes MellitusDiabetes Mellitus, Type 2Diabetes+8 more
University of Colorado, Denver240 enrolled2 locationsNCT07011147
Recruiting
Not Applicable

Michigan Men's Diabetes Project III(MenDIII): Mind and Motion

DepressionDiabetes Mellitus, Type 2Depressive Symptoms
University of Michigan80 enrolled1 locationNCT06574035
Recruiting
Phase 3

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Cardiovascular DiseasesHypertensionDiabetes Mellitus, Type 2
Boehringer Ingelheim11,800 enrolled1155 locationsNCT07064473
Recruiting
Not Applicable

AIM-MET: AI-Guided Microbiome-Targeted Nutrition for Glycemic Improvement in Type 2 Diabetes

Diabetes Mellitus, Type 2Type 2 Diabetes
ENBIOSIS BIOTECHNOLOGIES100 enrolled1 locationNCT07622628
Recruiting
Phase 4

A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels Compared to Daily Basal Insulins in Adults With Type 2 Diabetes

Diabetes Mellitus, Type 2
Novo Nordisk A/S586 enrolled75 locationsNCT07112339
Recruiting
Phase 2

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

ObesityDiabetes Mellitus, Type 2Overweight
Eli Lilly and Company200 enrolled42 locationsNCT07215559
Recruiting
Not Applicable

Diabetes Multimorbidity Typology, Trajectory, and Feasibility of an Audio Diary Mobile Application to Support Self-management

Diabetes Mellitus, Type 2Diabetes Mellitus, Type 1
Emory University30 enrolled1 locationNCT07474376
Recruiting
Not Applicable

Glucose and Activity Tracking for Sedentary Behavior Interventions in Older People With Type 2 Diabetes (TRACK T2D)

Diabetes Mellitus, Type 2
University of Minnesota60 enrolled1 locationNCT07524205
Recruiting
Phase 1

A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006)

Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC52 enrolled4 locationsNCT07242469
Recruiting
Not Applicable

Mobile Health and Wearable Devices for Diabetes Complication Management

Diabetes Mellitus, Type 2Diabetes Mellitus Complications
Second Xiangya Hospital of Central South University6,000 enrolled1 locationNCT07129148
Recruiting
Phase 4

Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetes

Diabetes Mellitus, Type 2Osteoarthritis, Knee
University of Kansas Medical Center120 enrolled1 locationNCT06478186
Recruiting
Not Applicable

Milk for Diabetes Prevention

Lactose intoleranceDiabetes Mellitus, Type 2Pre-diabetes+2 more
Albert Einstein College of Medicine40 enrolled1 locationNCT06513026
Recruiting
Phase 2

A Study of LY3938577 in Participants With Type 2 Diabetes Previously Treated With Basal Insulin

Diabetes Mellitus, Type 2
Eli Lilly and Company100 enrolled26 locationsNCT07215312
Recruiting
Phase 4

A Study of Tirzepatide (LY3298176) in Adult Participants in India With Either Type 2 Diabetes Mellitus or Obesity

ObesityDiabetes Mellitus, Type 2Overweight
Eli Lilly and Company344 enrolled21 locationsNCT07438444
Recruiting
Phase 2

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

Diabetes Mellitus, Type 2
Novo Nordisk A/S270 enrolled63 locationsNCT07415954
Recruiting
Phase 4

Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay.

ObesityDiabetes Mellitus, Type 2
Las Rías Medical Center160 enrolled1 locationNCT07588438
Recruiting
Phase 1

A Research Study to Evaluate the Safety of NNC1679-0001 When Given to Healthy Participants and Participants With T2DM

Diabetes Mellitus, Type 2Healthy Volunteers
Novo Nordisk A/S80 enrolled1 locationNCT07570992
Recruiting

AI-Based Phenome Data Analysis for Predicting the Onset of Major Diseases

Breast NeoplasmsCardiovascular DiseasesDiabetes Mellitus, Type 2+2 more
Jae Yong Jeon, MD1,000 enrolled1 locationNCT07595718
Recruiting
Not Applicable

Home-based Heat Therapy for Type 2 Diabetes

Diabetes Mellitus, Type 2Heat Exposure
Montreal Heart Institute44 enrolled1 locationNCT05269589