RecruitingNot ApplicableNCT06296875

The Krill Ageing Muscle Mechanisms (KAMM) Study

Uncovering the Mechanisms Through Which Krill Oil Increases Muscle Function in Older Adults.


Sponsor

University of Glasgow

Enrollment

80 participants

Start Date

Sep 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to determine the mechanisms via which krill oil supplementation increases muscle strength and whether this translates to improvements in gait and functional characteristics in older adults. The studies we will carry out will establish, in healthy older adults, the effects of 6 months of supplementation with krill oil Objective 1) Muscle structure and function Hypothesis: Krill oil supplementation will increase muscle size and strength alongside positive changes in muscle architecture (pennation angle and fascicle length). Objective 2) Neuromuscular control and central nervous system (CNS) function Hypothesis: Krill oil supplementation will improve Neuromuscular Junction (NMJ) transmission stability and increase central drive and intramuscular coherence, as a measure of muscle synergy. Objective 3) Gait and functional characteristics Hypothesis: Krill oil supplementation will improve gait and functional characteristics.


Eligibility

Min Age: 65 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Krill oil and Vegetable oil for people with sarcopenia. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTVegetable oil

mixed vegetable oil

DIETARY_SUPPLEMENTKrill oil

Krill oil


Locations(1)

University of Glasgow

Glasgow, United Kingdom

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NCT06296875


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