RecruitingNCT06299748

A Worldwide Pregnancy Safety Study to Assess Maternal, Fetal, and Infant Outcomes Following Exposure to Efgartigimod During Pregnancy and/or Breastfeeding.

A Worldwide Pregnancy Safety Study To Assess Maternal, Fetal, And Infant Outcomes Following Exposure To Efgartigimod During Pregnancy And/Or Breastfeeding


Sponsor

argenx

Enrollment

279 participants

Start Date

Nov 30, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This is a multi-country, prospective safety study of pregnant women exposed to efgartigimod or efgartigimod PH20 SC any time within 25 days prior to conception or any time during pregnancy. Women exposed to efgartigimod or efgartigimod PH20 SC only during breastfeeding will also be eligible to enroll. Background rates of major congenital malformations (MCMs) will be obtained from populations within the same countries/regions as the countries/regions in which the efgartigimod or efgartigimod PH20 SC exposed pregnancies were reported.


Eligibility

Sex: FEMALE

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called Efgartigimod for people with cidp - chronic inflammatory demyelinating polyneuropathy and myasthenia gravis. The study is currently recruiting participants at 4 locations. People eligible for this study include women.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALEfgartigimod

Efgartigimod IV or SC


Locations(4)

United BioSource LLC

Morgantown, West Virginia, United States

Klinikum der Ruhr-Universität Bochum St. Josef Hospital Neurologische Interdisziplinäre Infusionsambulanz + MS Studienambulanz (Haus E Ebene1)

Bochum, Germany

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Roma, Italy

Hospital Universitari Vall d'Hebron

Barcelona, Spain

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NCT06299748


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