Study of the Risk of Pharyngocutaneous Fistula in a Population of Patients Undergoing Total Laryngectomy and Creation of a Score for Pre-operative Risk Stratification.

This study looks at what factors increase the risk of developing a pharyngocutaneous fistula — a hole that can form between the throat and the skin after total laryngectomy (complete removal of the voice box). Researchers want to build a scoring tool that surgeons can use before the operation to identify high-risk patients. **You may be eligible if...** - You are scheduled for total laryngectomy (complete voice box removal) - Your surgery involves a laryngeal (voice box) tumor that is new, came back after prior surgery within the larynx, or came back after radiation or chemoradiation treatment - Your case involves a non-functioning voice box caused by radiation treatment **You may NOT be eligible if...** - Your surgery requires the use of a tissue flap (a piece of skin or muscle moved from another part of the body to help close the wound) - You have previously had surgery on the throat area above the voice box (hypopharynx or oropharynx) Talk to your doctor to see if this trial is right for you.