RecruitingNot ApplicableNCT06310330

TRUST-ACE - Anticancer-treatment Cardiotoxicity Identification by Echocardiography

Technology Revising Ultrasound Solutions for Tomorrow - Anticancer-treatment Cardiotoxicity Identification by Echocardiography

Sponsor

Norwegian University of Science and Technology

Enrollment

250 participants

Start Date

Mar 8, 2024

Study Type

INTERVENTIONAL

Conditions

Breast Neoplasm Malignant Primary

Summary

TRUST-ACE will compare a simplified echocardiographic protocol focusing on ventricular function with the guideline recommended comprehensive echocardiographic examination using a randomised design in follow-up of breast-cancer patients with respect to identification of cancer treatment related cardiac dysfunction (CTRCD). Secondly, the study will evaluate whether novel tools used to improve standardization of recordings as well as automated measurements of central measurements, e.g. ejection fraction (EF) and global longitudinal strain (GLS) can improve the precision of echocardiography in daily clinical practice.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study uses echocardiography (an ultrasound of the heart) to detect early heart damage in breast cancer patients who have received or are receiving cancer treatments that can be toxic to the heart — a condition called cancer treatment-related cardiac dysfunction (CTRCD). The goal is to catch heart problems early before symptoms develop. **You may be eligible if...** - You have been diagnosed with breast cancer - You have been referred for heart monitoring (echocardiogram follow-up) to check for possible heart damage related to your cancer treatment **You may NOT be eligible if...** - You are unwilling or unable to provide informed consent for participation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTComprehensive echocardiographic follow-up

Comprehensive echocardiographic follow-up for identification of CRTCD in breast cancer patients

DIAGNOSTIC_TESTSimplified echocardiographic follow-up

Simplified echocardiographic follow-up for identification of CRTCD in breast cancer patients

Locations(1)

St. Olavs hospital

Trondheim, Norway

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NCT06310330

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