A Dose Escalation Study of IG3018 in Subjects With Hyperuricemia With or Without Chronic Kidney Disease

This study tests a new drug called IG3018 to lower uric acid levels in people with hyperuricemia (too much uric acid in the blood), which can cause gout and kidney problems. The trial includes both people with normal kidney function and those with moderate to advanced chronic kidney disease (CKD). **You may be eligible if...** - You are between 18 and 75 years old - You have elevated uric acid levels in your blood (above 0.48 mmol/L) - Part 1: You have normal or near-normal kidney function - Part 2: You have chronic kidney disease, stage 3a through 4 (moderate to severe CKD, but not yet on dialysis) **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have severe heart, liver, or other serious medical conditions - You are currently taking certain other medications that interfere with the study drug - You are already on dialysis Talk to your doctor to see if this trial is right for you.