RecruitingNCT06315179

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation


Sponsor

Seattle Children's Hospital

Enrollment

200 participants

Start Date

May 10, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This is a prospective observational study collecting long-term clinical data and samples for research in pediatric inflammatory bowel disease (IBD) patients with gut inflammation and a control cohort of pediatric patients with disorders of the brain-gut interactions (DBGI) with no detectable gut inflammation.


Eligibility

Min Age: 6 YearsMax Age: 21 Years

Inclusion Criteria1

  • Suspected diagnosis of CD (Crohn's Disease), UC (Ulcerative Colitis) or Indeterminate colitis (IC)

Exclusion Criteria4

  • Evidence of Other Complicating Medical Issues:
  • Other serious medical conditions, such as neurological, liver, kidney, or systemic disease
  • Pregnancy
  • Tobacco, alcohol, or illicit drug abuse

Interventions

DIAGNOSTIC_TESTEsophagogastroduodenoscopy (EGD) with biopsy

Esophagogastroduodenoscopy (EGD) is a test procedure to examine the lining of the esophagus, stomach, and first part of the small intestine.

DIAGNOSTIC_TESTColonoscopy w/ biopsy

Colonoscopy is a test procedure to examine the lining of the different portions of the large intestine: cecum, colon, rectum, and anal canal.


Locations(1)

Seattle Children's Hospital

Seattle, Washington, United States

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NCT06315179


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