Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

This study (called STRIDE) is collecting detailed tissue samples from patients with inflammatory bowel disease (IBD) — including Crohn's disease, ulcerative colitis, and indeterminate colitis — to analyze the spatial patterns of gene expression within the gut tissue. This advanced technique (spatial transcriptomics) allows researchers to map exactly which cells are active in which areas of inflamed tissue, helping understand why IBD develops and how to better treat it. **You may be eligible if...** - You have a suspected diagnosis of Crohn's disease, ulcerative colitis, or indeterminate colitis **You may NOT be eligible if...** - You have other serious medical conditions such as significant neurological, liver, kidney, or systemic disease - You are pregnant - You have active tobacco, alcohol, or illicit drug use Talk to your doctor to see if this trial is right for you.