RecruitingNCT06318585

Creation of a Clinical Database for the Study of Phenotypic Variability in Motor Neuron Diseases

Creazione di un Database Clinico Per lo Studio Della variabilità Fenotipica Nella Malattia Del Motoneurone


Sponsor

Istituto Auxologico Italiano

Enrollment

200 participants

Start Date

Apr 3, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Study Description: Characterization of Motor Neuron Disease Phenotypes The goal of this observational study is to understand the clinical presentation of motor neuron disease (MND) in patients attending the Neurology Department of the Istituto Auxologico Italiano. The main questions it aims to answer are: * What are the specific clinical phenotypes associated with MND? * How can these phenotypes contribute to a better understanding of the disease's underlying mechanisms and improve prognostic accuracy? Participants will undergo: * Clinical evaluation using validated scales * Neurophysiological and neuroradiological instrumental assessment * Neuropsychological evaluation * Collection of biological materials for genetic screening and biomarker assessment, if necessary.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • diagnosis of ALS or other motor neuron disease

Exclusion Criteria1

  • refusal to participate to the study

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Locations(1)

Ospedale San Luca

Milan, MI, Italy

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NCT06318585


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