FLuorescence Guided Assessment of Mesenteric Ischemia in Emergency Surgery
Intraoperative Intestinal Perfusion Assessment by Fluorescence Angiography in Emergency Surgery
Rigshospitalet, Denmark
100 participants
Mar 5, 2024
INTERVENTIONAL
Conditions
Summary
This is a prospective, multicentre, non-randomized cohort study using real-time intraoperative visualization of bowel perfusion by indocyanine green (ICG) in all-cause bowel ischemia. At intraoperative finding of bowel ischemia, the initial intraoperative plan is noted and resection margins marked with a steril pen. A fluorescence angiography will be performed and the surgeon will note whether the suspected ischemic bowel is perfused, whether there is a change in the resection margins in centimeters, and if the intraoperative plan has changed. If resection is indicated and the strategy of choice is an anastomosis, a renewed fluorescence angiography will be performed to assess anastomotic perfusion.
Eligibility
Inclusion Criteria3
- Adult patients \>18 years of age
- Acute physiologic derangement and suspected of having bowel ischemia
- Intraoperative finding of all-cause bowel ischemia with subsequent acute physiologic derangement
Exclusion Criteria5
- Allergy toward; iodine, indocyanine green, or shellfish
- Liver insufficiency
- Thyrotoxicosis
- Pregnancy or lactation
- Permanently legally incompetent for any reason
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Interventions
Intraoperative perfusion assessment with ICG Fluorescence Angiography (ICG-FA) in standard approved doses
Locations(5)
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NCT06322862