RecruitingNCT06329414

Acceptability and Feasibility of Transcranial Magnetic Stimulation (TMS) for Depression in Multiple Sclerosis


Sponsor

University of Utah

Enrollment

12 participants

Start Date

Jan 16, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this single-arm, observational pilot study is to learn about the safety, feasibility, preliminary efficacy of TMS for the treatment of depression in people with MS. Participants will receive outpatient TMS treatment over the course of 5-6 weeks. Participants will complete validated questionnaires and exams before, during, and after treatment.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria3

  • Established diagnosis of multiple sclerosis (any subtype) by 2017 McDonald criteria
  • Established diagnosis of major depressive disorder (MDD) by DSM-5 criteria
  • Eligible for transcranial magnetic stimulation (rTMS) for depression

Exclusion Criteria5

  • MS relapse and/or steroid use within 3 months
  • Active suicidal ideation
  • History of seizure/epilepsy, brain tumor, or stroke
  • History of bipolar disorder or psychosis
  • Currently or planning to become pregnant

Locations(1)

University of Utah Health

Salt Lake City, Utah, United States

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NCT06329414


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