Effect of Ketosteril on Sarcopenia in Patients With Chronic Kidney Disease

This study is testing whether a supplement called Ketosteril (a combination of amino acid building blocks) can help people with chronic kidney disease (CKD) who are also experiencing muscle loss and weakness — a condition known as sarcopenia. Muscle loss is common in people with CKD and can significantly affect quality of life. Researchers want to see if Ketosteril can help preserve or restore muscle strength and function. **You may be eligible if:** - You have been diagnosed with stage 3 or 4 chronic kidney disease (moderate to severe) - You have been diagnosed with sarcopenia, meaning you have reduced muscle mass AND either weak grip strength or difficulty walking or standing up from a chair - You are able to walk independently **You may NOT be eligible if:** - You have diabetes - You are overweight or obese (BMI greater than 25) - You have previously had kidney dialysis or a kidney transplant - You had a major heart event or uncontrolled heart failure in the last 3 months - You have an active infection or uncontrolled flare-up of another illness - You have had a stroke, severe liver disease, cancer, or multiple organ failure - You have joint disease, bone disease, paralysis, or significant cognitive decline that limits movement - You have high blood calcium levels or amino acid metabolism disorders - You are allergic to any ingredient in Ketosteril - You participated in another clinical trial in the past 30 days Talk to your doctor to see if this trial is right for you.