Treatment of Pulmonary SUlcus, Pancoast and Chest Wall Non-small Cell Lung Cancer Employing Radiation, Immuno-oncology and Resection

This study is testing a combination treatment — radiation therapy, immunotherapy, and surgery — for a rare and aggressive type of non-small cell lung cancer called Pancoast or pulmonary sulcus tumor, which grows in the top part of the lung and often invades nearby chest structures. Researchers want to know if adding immunotherapy (a drug that activates the immune system to fight cancer) before and after surgery alongside radiation can improve outcomes. **You may be eligible if:** - You are 18 or older in good overall health (ECOG 0 or 1) - You have a confirmed Pancoast or chest wall non-small cell lung cancer that is potentially removable by surgery - You weigh more than 30 kg - Your blood counts, liver, and kidney function meet required levels - You are willing to follow the full treatment and follow-up schedule **You may NOT be eligible if:** - Your cancer has spread extensively beyond the local area - You have significant heart, liver, kidney, or other organ problems - You have had prior radiation to the affected area - Your life expectancy is less than 12 weeks Talk to your doctor to see if this trial is right for you.