INSIDE: Identification of Genomic Screening Pathways in Cancer Patients With DNA Repair Alterations

This study is examining the genetic makeup of prostate cancer across different stages — from early high-risk disease to advanced metastatic stages — to identify markers that could predict how a patient will respond to treatment or whether the cancer will return. **You may be eligible if...** - You are over 18 years old - You have prostate cancer in one of three categories: high-risk localized disease, newly diagnosed metastatic hormone-sensitive prostate cancer, or metastatic castration-resistant prostate cancer - Tumor tissue from a biopsy or surgery is available for genetic analysis - You have not yet started standard treatment, or started within the last 3 months (depending on the cohort) **You may NOT be eligible if...** - Sufficient tumor tissue is not available for genomic analysis - You do not consent to genetic testing of your tumor Talk to your doctor to see if this trial is right for you.