Possible Efficacy and Safety of Mebendazole in Patients With Ulcerative Colitis Treated With Mesalamine

This study is testing whether mebendazole — a common anti-parasitic medication — may also help treat mild to moderate ulcerative colitis (a type of inflammatory bowel disease that causes chronic gut inflammation), when added to standard treatment. **You may be eligible if...** - You are 18 years or older (male or female) - You have been diagnosed with mild to moderate ulcerative colitis, confirmed by colonoscopy - You are currently being treated with mesalamine (5-aminosalicylic acid) **You may NOT be eligible if...** - You have severe ulcerative colitis - You have significant liver or kidney problems - You have diabetes - You have colorectal cancer - You are using steroids, immunosuppressants, or biological therapies - You have heart disease or congestive heart failure - You are allergic to mebendazole or similar medications - You have had part or all of your colon removed Talk to your doctor to see if this trial is right for you.