RecruitingNot ApplicableNCT06335719

Intraoperative Electrical Stimulation to Improve Nerve Grafting Outcome

Intraoperative Brief Electrical Stimulation to Improve Cross-Face Nerve Grafting Outcomes


Sponsor

The Cleveland Clinic

Enrollment

20 participants

Start Date

Mar 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

A research study to find out if brief intraoperative electrical stimulation therapy improves nerve regeneration and smile outcomes following two-stage cross face nerve graft facial reanimation surgery.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria2

  • Patients 18-80 years-old with unilateral facial paralysis who are candidates for two- stage CFNG smile reanimation surgery (i.e. CFNG-driven free gracilis muscle transfer (FGMT) or dual innervation FGMT).
  • Agree to participate in the study.

Exclusion Criteria3

  • Bilateral facial paralysis
  • Age less than 18 years-old or older than 80 years-old
  • Comorbid medical condition preventing two-stage CFNG surgery

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Interventions

PROCEDUREBES

Nerve biopsies during surgery + brief electrical stimulation therapy

PROCEDUREStandard of Care surgery

Nerve biopsies during surgery - no brief electrical stimulation therapy


Locations(1)

Cleveland Clinic Foundation

Cleveland, Ohio, United States

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NCT06335719


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