RecruitingNCT06337149

Relationship Between Breathing and Attention in Children With Ondine Syndrome


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

20 participants

Start Date

Feb 29, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Congenital central hypoventilation syndrome (CCHS) is a rare disorder of autonomic and respiratory regulation that alters oxygen delivery to the brain. CCHS patients are at risk for broad neurocognitive deficits. Patients retain ventilatory activity when awake through a respiratory-related cortical network but the need to mobilise cortical resources to breathe lead to breathing-cognition interferences during cognitive tasks. The purpose of this study is to assess the relationship between breathing pattern and attention in CCHS children


Eligibility

Min Age: 6 YearsMax Age: 16 Years

Inclusion Criteria1

  • children with CCHS (Ondine Syndrome) and IQ > 70, age from 6 to 16 years old, french speaking, informed consent signed by both parents and oral agreement in principle given by the subject.

Exclusion Criteria1

  • IQ < 70

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Interventions

OTHERneuropsychological tests used usually in clinical practice (TEA-ch, NEPSY, BRIEF) and research (Conners 3, K-CPT II or CPT III, Flankers Task)

neuropsychological tests used usually in clinical practice (TEA-ch, NEPSY, BRIEF) and research (Conners 3, K-CPT II or CPT III, Flankers Task)


Locations(1)

Robert Debre Hospital

Paris, France

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NCT06337149