Study of the Prevalence of Autistic Traits in Angelman Syndrome
Study of the Prevalence of Autistic Traits in Angelman Syndrome, the Correlation With Cognitive Level, Epilepsy, With Socio-communication Skills and Parenting Styles
IRCCS Eugenio Medea
46 participants
Mar 15, 2022
OBSERVATIONAL
Conditions
Summary
The goal of this observational cross-sectional study is to establish the prevalence of autism spectrum disorder in children and adolescents with Angelman syndrome. The main questions it aims to answer are: * which clinical variables differentiate AS patients with and without Autism Spectrum Disorder between genetics, epilepsy, pharmacotherapy, behavioural problems, parenting style and parents' perceived stress. * which clinical variables differentiate parenting styles and levels of perceived stress. Data from neuropsychological, speech therapy and physiotherapeutic assessments are collected during regular clinical follow-ups, regarding: cognitive development ("Bayely Scales of Infant Development-III", Cognitive Scale) and adaptive behaviour; Autism and Autism Spectrum Disorder ("Autism Diagnostic Observational Schedule-2"); parental stress and parenting styles; social-communicative skills; motor development.
Eligibility
Inclusion Criteria2
- genetically confirmed diagnosis of Angelman Syndrome
- chronological age between 4-15 years
Exclusion Criteria3
- genetic examination pending report
- mental age lower than 12 months
- brain injury acquired in the peri- or postnatal period
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06337383