RecruitingNCT06338696

Thailand ATTR-CM Registry

Thailand Transthyretin Amyloid Cardiomyopathy Registry

Sponsor

Mahidol University

Enrollment

105 participants

Start Date

Jul 30, 2024

Study Type

OBSERVATIONAL

Conditions

Transthyretin Amyloid Cardiomyopathy (ATTR CM)

Summary

The investigators of this registry aim to study the natural history, clinical presentation, characteristics, and imaging findings of patients diagnosed with ATTR amyloidosis in Thailand longitudinally. This will enable the investigators to study this disease in depth. With a better understanding, the investigators can aim to develop early screening programs for at-risk patients, raising awareness among non-cardiologists. As amyloid-specific therapies have now become available in Thailand, the findings of this registry can be helpful for epidemiological studies in Thailand.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This is a registry study (data collection, not a treatment trial) tracking patients in Thailand who have been diagnosed with ATTR cardiomyopathy — a heart condition caused by a protein called transthyretin building up in the heart muscle, making it stiff and weak. **You may be eligible if...** - You are over 18 years old - You have been diagnosed with ATTR cardiomyopathy, confirmed by specific heart imaging scans (bone scan or cardiac MRI) showing thickened heart walls (12 mm or more) and other diagnostic criteria - You may have symptoms or be asymptomatic (no symptoms yet) **You may NOT be eligible if...** - Your amyloidosis is caused by a protein other than transthyretin (e.g., light chain amyloidosis) - You have other forms of amyloid heart disease not related to transthyretin Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERNo intervention

No intervention

Locations(8)

Faculty of Medicine at Chulalongkorn University

Bangkok, Thailand

Faculty of Medicine Ramathibodi hospital, Mahidol University

Bangkok, Thailand

Faculty of Medicine Siriraj Hospital, Mahidol University

Bangkok, Thailand

Phramongkutklao Hospital

Bangkok, Thailand

Faculty of Medicine Chiang Mai University

Chiang Mai, Thailand

Queen Sirikit Heart Center of The Northeast

Khon Kaen, Thailand

Faculty of Medicine, Thammasat University

Pathum Thani, Thailand

Prince of Songkla University

Songkhla, Thailand

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NCT06338696

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