RecruitingNot ApplicableNCT06340945

The Outcomes of Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules

The Clinical Outcomes and Artificial Intelligence Prediction Model of Ultrasound-guided Thermal Ablation for the Treatment of Benign Thyroid Nodules：A Multicenter Prospective Study

Sponsor

Chinese PLA General Hospital

Enrollment

1,500 participants

Start Date

Apr 1, 2024

Study Type

INTERVENTIONAL

Conditions

Thyroid Nodules

Summary

1. To evaluate the clinical outcomes of ultrasound-guided thermal ablationfor the treatment of benign thyroid nodules; 2. To develop and validate a artificial intelligence model to predict the outcomes of ultrasound-guided thermal ablation in the treatment of benign thyroid nodules

Eligibility

Min Age: 18 Years

Inclusion Criteria1

\[1\]confirmation of benign nodule status on two separate fine- needle aspiration (FNA) or core-needle biopsy (CNB) \[2\]no suspicious malignant features on ultrasound examination \[3\]report of cosmetic and/ or symptomatic problems or concern of nodules growing rapidly or malignant transformation \[4\]refusal or ineligibility for surgery \[5\]follow-up time ≥6months

Exclusion Criteria6

follicular neoplasm or malignancy findings on biopsy
nodules with benign result on biopsy had suspicious of malignancy in US, including marked hypoechoic, ill-defined margins, taller-than-wide shape or microcalcifications
patients with cystic nodules
patients with contra-lateral vocal cord par- alysis
previous radiation to the head and neck
; follow- up time less than 6 months