RecruitingNot ApplicableNCT06344962

Clinical Effects of Absorbable and Non-absorbable Suture in Bronchial Sleeve Resection

Comparison of Clinical Effects of Absorbable and Non-absorbable Suture in Bronchial Sleeve Resection


Sponsor

The Affiliated Hospital of Qingdao University

Enrollment

40 participants

Start Date

Feb 28, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Bronchial sleeve resection is performed as an alternative to pneumonectomy for lung cancer patients with centrally located lesions and limited cardiopulmonary reserve. Intraoperative bronchial anastomosis is very complex and difficult, mainly due to the difficulty of suturing and knotting in limited space. There are currently few studies comparing the clinical effects of absorbable and non-absorbable suture in bronchial sleeve resection. So the investigator wants to conduct a prospective study, trying to figure out this problem.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria7

  • Age 18 to 75 years old.
  • The tumor is located in the opening of bronchus, or the edge of the tumor is less than 2 cm away from the opening of the bronchi, while the distance between the edge of the tumor and the carina is more than 1.5 cm.
  • Patients with pathological diagnosis of non-small cell lung cancer.
  • No distant metastasis in preoperative clinical evaluation.
  • Adequate cardiac function, pulmonary function, liver function and renal function for anesthesia and bronchial sleeve resection.
  • American Society of Anesthesiologists (ASA) score: Grade I-III.
  • Patients who can coordinate the treatment and research and sign the informed consent.

Exclusion Criteria2

  • Patients with a significant medical condition which is thought unlikely to tolerate the surgery or unsuitable for this study after the evaluation of the investigator.
  • Patients with psychiatric disease who are expected lack of compliance with the protocol.

Interventions

DEVICEAbsorbable Suture

3-0 V-Loc

DEVICENon-absorbable Suture

3-0 Prolene


Locations(1)

the Affiliated Hospital of Qingdao University

Qingdao, Shandong, China

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NCT06344962