RecruitingNot ApplicableNCT06351696

The Effects of Bromelain Supplement in Patients With Ulcerative Colitis

The Effects of Low FODMAP Diets Accompanied With and Without Bromelain Supplement on Quality of Life, Disease Activity Index and Inflammation in Patients With Ulcerative Colitis With and Without Primary Sclerosis Cholangitis

Sponsor

National Nutrition and Food Technology Institute

Enrollment

84 participants

Start Date

Apr 20, 2024

Study Type

INTERVENTIONAL

Conditions

Ulcerative Colitis Primary Sclerosing Cholangitis

Summary

In this study, patients with active mild to moderate UC with or without PSC will be randomized to receive either bromlein or placebo along with low FODMAP diet for 8 weeks. IBDQ, SCCAIQ, CRP, TAC, TNF-a will be measured before and after the intervention.

Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether taking bromelain — a natural enzyme found in pineapple — as a dietary supplement helps reduce symptoms in people with active ulcerative colitis (UC), a chronic inflammatory disease of the large intestine. **You may be eligible if...** - You have been diagnosed with ulcerative colitis - Your disease is currently active and mild to moderate in severity - You do not have other chronic health conditions **You may NOT be eligible if...** - You recently changed your medication type or dose (within the past month) - You experienced a severe relapse that required hospitalization and medication changes during the study - You are unwilling to follow the study protocol Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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