RecruitingNCT06352216

Prevalence of Synovitis in Patients With Haemophilia A

Prevalence of Synovitis in Adult Patients With Haemophilia A in Germany and Austria


Sponsor

University Hospital, Bonn

Enrollment

300 participants

Start Date

Apr 15, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this study is to evaluate the prevalence of synovitis in adult patients with haemophilia A.


Eligibility

Sex: MALEMin Age: 18 Years

Inclusion Criteria3

  • Participants (≥ 18 years old) suffering from moderate or severe haemophilia A, also with inhibitor or joint replacement
  • Complete documentation of hemophilia severity, treatment history (past 12 months), and bleeding events (past 12 months), inhibitor status (at time of enrollment and in past medical history)
  • Submitted written consent to participate in the study

Exclusion Criteria2

  • Patients suffering from other bleeding disorders conflicting with the research question
  • Patients in clinical studies with investigational drugs

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Interventions

DIAGNOSTIC_TESTHemophilia Early Arthropathy Detection with Ultrasound (HEAD-US); Haemophilia joint health score (HJHS)

Each subject is examined for the presence of synovitis using the aforementioned diagnostics.


Locations(1)

University Hospital Bonn

Bonn, North Rhine-Westphalia, Germany

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NCT06352216


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