RecruitingNCT06353191

Biomarkers to Predict Cancer Therapy-related Cardiotoxicity

Biomarkers to Predict Cancer Therapy-Related Cardiotoxicity


Sponsor

Mayo Clinic

Enrollment

1,000 participants

Start Date

May 3, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

This study evaluates why some cancer patients but not others experience changes in heart function following treatment with chemotherapy.


Eligibility

Min Age: 18 Years

Inclusion Criteria8

  • years of age or older
  • Treated for any malignancy with any type of chemotherapy including oral, parenteral therapy and immunotherapy
  • One of the following:
  • Diagnosed with cardiotoxicity defined as; cardiomyopathy, symptomatic heart failure, asymptomatic reduced systolic function, acute coronary syndrome, myocardial infarction, critical limb ischemia, cardiac arrhythmias or myocarditis possibly related to prior cancer treatment
  • Completed chemotherapy with no cardiotoxicity at least two years post treatment
  • Patients with cancer who will be initiating systemic therapy with potentially cardiotoxic medications. This will include chemotherapy, immunotherapy, targeted therapy that have been associated with cardiac toxicity
  • An understanding of the protocol and its requirements, risks, and discomforts
  • The ability and willingness to sign an informed consent

Exclusion Criteria1

  • \- Inability on the part of the patient to understand the informed consent or be compliant with the protocol

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Interventions

OTHERNon-Interventional Study

Non-interventional study


Locations(4)

Mayo Clinic in Arizona

Scottsdale, Arizona, United States

Mayo Clinic in Florida

Jacksonville, Florida, United States

Moffitt Cancer Center

Tampa, Florida, United States

Mayo Clinic in Rochester

Rochester, Minnesota, United States

View Full Details on ClinicalTrials.gov

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NCT06353191


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