RecruitingNCT06353789

Adolescent Dysmenorrhoea as a Risk Factor for Chronic Pain: Clinical Cohort Study

Understanding the Role of Adolescent Dysmenorrhoea as a Risk Factor for the Transition to Chronic Pain: Clinical Cohort Study


Sponsor

University of Oxford

Enrollment

132 participants

Start Date

Jun 4, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to understand whether changes in a variety of body systems which are seen in adult women with period pain are also seen in adolescents in the first few years of having periods. This information will help to understand 1) how quickly any changes occur, informing clinical practice, and 2) how period pain might lead to other types of chronic pain, potentially allowing development of preventative strategies.


Eligibility

Sex: FEMALEMin Age: 11 YearsMax Age: 20 Years

Inclusion Criteria11

  • Participant (or parent/guardian of participant) is willing and able to give informed consent for participation in the study.
  • Female or assigned female at birth.
  • aged 11 - 20 years.
  • At least 6 periods per year since menarche.
  • During the study data collection period will be within one of the following time intervals since menarche:
  • - 15 months
  • - 39 months
  • - 63 months
  • Reports either period pain or no pain with periods and scores appropriately on NRS (period pain: ≥4/10; no period pain: ≤3/10).
  • Not using hormonal therapies (i.e. contraceptives) currently and has not used previously.
  • Reasonably fluent in English.

Exclusion Criteria4

  • Current or previous chronic pain condition other than dysmenorrhoea, including migraine.
  • Pregnant or breast-feeding.
  • Previous cancer diagnosis.
  • Contraindication to MRI

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Locations(1)

University of Oxford

Oxford, Oxfordshire, United Kingdom

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NCT06353789


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