Effect of Intravenous Vitamin C on Intrapartum Maternal Fever After Epidural Labor Analgesia
Effect of Intravenous Vitamin C on Intrapartum Maternal Fever After Epidural Labor Analgesia : A Randomized Controlled Trial
Kunyue Li
400 participants
Apr 15, 2024
INTERVENTIONAL
Conditions
Summary
This study aims to explore the effect of intravenous vitamin C infusion on intrapartum fever after epidural labor analgesia, to reduce the impact of intrapartum fever on maternal and infant, improve maternal and infant outcomes, and provide a reference for clinical preventive medication.
Eligibility
Inclusion Criteria1
- single-fetus, head position, and full-term vaginal delivery receiving epidural labor analgesia.
Exclusion Criteria1
- have a fever before epidural analgesia, acute infection on admission, incomplete baseline data, fatal fetal malformations or comorbidities, duration from admission to delivery of more than 72 hours or less than 3 hours, or an American Society of Anesthesiologists (ASA) classification of ≥ Ⅲ.
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Interventions
Drug Specification: 5ml: 1g. Method: parturients in each group will be intravenously injected with corresponding dose after receiving epidural labor analgesia.
The placebo comparator will receive normal saline with the same volume and be administered after the induction of epidural labor anesthesia.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06354582