RecruitingNCT06354881

The Relationship Between Controlling Risk Factors and Cerebral Haemodynamics in Lacunar Stroke

Understanding the Relationship Between Controlling Risk Factors and Cerebral Haemodynamic Changes in Lacunar Stroke, and Its Interaction With Ageing


Sponsor

University of Leicester

Enrollment

75 participants

Start Date

May 2, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to look at differences in brain blood flow before and after management of risk factors such as high blood pressure and diabetes in patients with lacunar stroke. Participants will be asked to undergo a simple brain blood flow assessment at their initial appointment, whereby they will be asked to sit and stand twice. The patients will then be asked for a follow-up assessment 4 weeks after, identical to the first. This will allow us to look at any changes in brain blood flow from before management of risk factors and 4 weeks after management of risk factors.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Transcranial Doppler Ultrasonography (TCD) during sit-stand manoeuvres for people with lacunar stroke. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICETranscranial Doppler Ultrasonography (TCD) during sit-stand manoeuvres

TCD will be used to measure the cerebral blood flow in the middle and posterior cerebral arteries. This will be done at rest and during two sit-stand manoeuvres, whereby the participant will be asked to stand (from a seated position) and stay standing for 1 minute. The participant will then be given time to recover before repeating the manoeuvre. This will occur at the first visit and the follow-up visit 4 weeks after.


Locations(1)

University Hospitals of Leicester NHS Trust

Leicester, Leicestershire, United Kingdom

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NCT06354881


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