Liver Volume Variation Effect on SBRT Planning and Delivery for Upper Abdominal Malignancies
The Effect of Liver Volume Variation on Stereotactic Body Radiation Therapy (SBRT) Planning and Delivery for Upper Abdominal Malignancies
University of Pittsburgh
17 participants
May 16, 2024
INTERVENTIONAL
Conditions
Summary
Standard planning constraints for liver SBRT incorporate strict dose-volume limits for normal liver parenchyma to minimize the risk of radiation-induced liver disease. The presence of diurnal and fasting/fed variations in liver volume therefore carry substantial potential for introducing errors into estimates of dose-volume distribution within normal liver tissue, as well as affecting day-to-day setup fidelity and organ alignment for treatment. This prospective study will examine how diurnal and fast-fed variations in liver volume affect treatment planning for abdominal SBRT.
Eligibility
Plain Language Summary
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Interventions
8 ounces of Ensure® nutritional protein shake or a similar meal
Locations(1)
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NCT06355895