RecruitingNCT06356545

Phenotype and Multi-omics Analysis of Children With Congenital Diarrhea and Enteropathy in China

A Case-control Study of Phenotype and Multi-omics Analysis of Children With Congenital Diarrhea and Enteropathy in China


Sponsor

Children's Hospital of Fudan University

Enrollment

60 participants

Start Date

Apr 15, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This study will establish a clinical cohort of children with congenital diarrhea and enteropathy (CODE), mine biomarkers of CODE through multi-omics technology and construct a clinical risk prediction model.


Eligibility

Min Age: 1 MonthMax Age: 3 Years

Inclusion Criteria2

  • Patients with chronic diarrhea lasting greater than 2 months or greater than 1 month in patients younger than 2 months of age
  • Patients with consent from parents or legal guardians

Exclusion Criteria4

  • Chronic diarrhea caused by specific infections, i.e. CMV, Clostridioides difficile
  • Chronic diarrhea with necrotizing enterocolitis, short bowel syndrome
  • Functional diarrhea
  • Patients with poor compliance

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Locations(1)

Yanqiu Wang

Shanghai, Shanghai Municipality, China

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NCT06356545


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