RecruitingNCT06357403

Association of Anti-factor Xa Activity With Venous Thromboembolism in Critically Ill Patients

Association of Anti-factor Xa Activity With Venous Thromboembolism in Critically Ill Patients: a Prospective Multicentre Cohort Study


Sponsor

Medical University of Vienna

Enrollment

1,300 participants

Start Date

May 4, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to analyse the association between anti-factor Xa activity (antiXa) and the occurence of venous thromboembolism (VTE; either deep vein thrombosis and/or pulmonary embolism) in critically ill patients who are admitted to an intensive care unit. The main questions it aims to answer are: * What is the association between antiXa and VTE? * What is the association between antiXa and symptomatic, respectively incidental, VTE? * How is pharmacological anticoagulation with enoxaparin related to measured antiXa? * What is the association between antiXa and bleeding complications. * What is the incidence of venous thromboembolism in patients treated at an intensive care unit? * How is the occurence of VTE related to patient-centred outcomes such as mortality, quality of life, length of stay and days outside of the intensive care unit/hospital.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Anti-factor Xa activity calibrated for enoxaparin for people with enoxaparin, pulmonary embolism, and other related conditions. The study is currently recruiting participants at 3 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTAnti-factor Xa activity calibrated for enoxaparin

Anti-factor Xa activity calibrated for enoxaparin


Locations(3)

Department of Internal Medicine, Medical University of Graz

Graz, Styria, Austria

Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck

Innsbruck, Tyrol, Austria

Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna

Vienna, Austria

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NCT06357403


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