RecruitingNot ApplicableNCT06360939

Radiotherapy vs Catheter Ablation for Ventricular Tachycardia in Structural Heart Disease


Sponsor

Western Sydney Local Health District

Enrollment

60 participants

Start Date

Nov 3, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this randomized clinical trial is to test the efficacy of stereotactic body radiation therapy (SBRT) in treating ventricular tachycardia (VT) in patients with advanced structural heart disease. The main questions it aims to answer are: * What is the efficacy of SBRT compared to catheter ablation (CA) in achieving a ≥ 75% reduction in VT burden at 6 months * What is the comparable safety profile of SBRT vs CA Researchers will compare SBRT and CA (standard of care).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called CA and SBRT for people with arrhythmias, cardiac, cardiomyopathies, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONSBRT

Delivery of 25Gy in a single dose fraction to target area within 6 weeks of randomization

PROCEDURECA

CA (endocardial and/or epicardial at operator discretion) within 6 weeks of randomization.


Locations(1)

Westmead Hospital

Westmead, Australia

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NCT06360939


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