RecruitingNCT06364579

Patient Reported Outcomes (PROs) in Anal Cancer Patient Treated by Intensity Modulated Radiotherapy (IMRT).


Sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Enrollment

120 participants

Start Date

Mar 28, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Radiochemotherapy is the standard treatment for neoplasms of the anal canal with excellent rates of local control and preservation of the anal sphincter. However, patients may experience a deterioration of quality of life related to sequelae of the treatment particularly at intestinal, anal sphincter and sexual level. Few studies to date have documented patient-reported outcomes (PROs) in this area. The aim of this observational study is to verify the quality of life (QOL) of the patients by means of self-completed questionnaires.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study collects information about the quality of life and symptoms reported by patients with anal cancer who are receiving a modern form of radiation therapy called intensity-modulated radiation therapy (IMRT), which delivers precise doses to target tumors while protecting nearby healthy tissue. **You may be eligible if...** - You are at least 18 years old - You have squamous cell carcinoma of the anal canal - You have a low amount of cancer spread (limited metastatic disease) - You are scheduled to receive combined chemotherapy and radiation therapy (radiochemotherapy) - Your general health allows for this treatment (ECOG 0–3) **You may NOT be eligible if...** - You are under 18 years old - Your general health is too poor (ECOG above 3) - Your cancer has spread widely and is not suitable for radiochemotherapy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Fondazione Policlinico Universitario A. Gemelli IRCCS

Rome, Lazio, Italy

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NCT06364579