RecruitingEarly Phase 1NCT06370845

ABUNDANCE of A NATURAL ODOUR in HUMAN CEREBROSPINAL FLUID AFTER OLFACTORY EXPOSURE - the OLFO-Brain Study

Abundance of a Natural Odour in Human Cerebrospinal Fluid After Olfactory Exposure - the OLFO-Brain Study


Sponsor

University Hospital, Basel, Switzerland

Enrollment

32 participants

Start Date

Apr 14, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to investigate the abundance of a natural odour in human cerebrospinal fluid in obese and lean participants after inhalation thereof. Participants will undergo blood sample collection and inhalation of either a natural odour or placebo through an inhaler in addition to a liquor puncture prescribed in standard of care context.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Inhalation - Natural Odour and Inhalation - Placebo for people with overweight and obesity. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years to 60 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

COMBINATION_PRODUCTInhalation - Natural Odour

Inhalation of 50 uL of a natural odour via nasal septum mini-inhaler.

COMBINATION_PRODUCTInhalation - Placebo

Inhalation of 50 uL of Placebo via nasal septum mini-inhaler.


Locations(2)

University Hospital Basel

Basel, Switzerland

University Hospital of Basel

Basel, Switzerland

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NCT06370845


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