Post Pandemic Pneumococcal Carriage Among Children and Adults
Post-Pandemic Genomic Epidemiology of Pneumococcal Carriage Among Children and Adults in the General US Population
University of Central Florida
900 participants
Jun 12, 2024
OBSERVATIONAL
Conditions
Summary
The PI propose to conduct a genomic epidemiology study of pneumococcal carriage among children and adults in a large metropolitan city. These data will allow PI to assess the post-pandemic population structure, investigate the phylogenetic relationship between isolates from children and adults, and compare pneumococcal populations across diverse geographic areas.
Eligibility
Inclusion Criteria5
- Children, ages 7 to 59 months (less than 5 years)
- Adults, ages 50 and older
- Ability to provide informed consent (from parents for children participants)
- ability to read and speak in English
- Agree to comply with study procedures (complete online data questionnaire and provide a nasopharyngeal collection).
Exclusion Criteria4
- Have been on an antibiotic in the last 2 weeks
- Have a respiratory infection that would make an nasopharyngeal collection improbable
- Have underlying developmental or chronic conditions impacting immune or respiratory function (e.g., immunocompromised, cystic fibrosis, cerebral palsy, paralysis)
- Adults unable to consent, individuals who are not yet adults, and prisoners will be excluded from this study.
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06373328