Role of Calcium Chloride Injection in Alleviating Atrial Fibrillation Post CABG
Post Operative Atrial Fibrillation: Alleviation by Calcium Chloride Injection Into Cardiac Ganglionic Plexus During Coronary Artery Bypass Grafting.
Helwan University
100 participants
Mar 14, 2024
INTERVENTIONAL
Conditions
Summary
This study hypothesize that injecting calcium chloride (CaCl2) into the major atrial ganglionated plexus (GPs) during on pump Coronary artery bypass graft (CABG) can reduce the incidence of Post operative Atrial fibrillation in the first 7 days after surgery.The study is designed to be prospective interventional study two armed RCT for on pump CABG patient. The intervention arm will be injected with Calcium chloride in the four major atrial ganglionic plexus The control arm will be injected with sodium chloride to determine the effect of Calcium chloride on Post CABG Atrial fibrillation
Eligibility
Inclusion Criteria1
- \) Patients more than 18 years old 2 ) patients undergoing On pump CABG
Exclusion Criteria4
- patients \>75 years of age
- Patients with Pre operative Atrial fibrillation
- Patients with Significant valvular disease
- \. Ejection fraction \<30% 6. Combined surgery of any kind 7. Congenital heart disease 8. Abnormal severe liver or kidney dysfunction. 9. Patients undergoing Off-pump CABG 10. Poorly controlled hyperthyroidism 11. Refusal to enrollment.
Interventions
5 % calcium chloride injection in cardiac ganglionic Plexus during On pump Coronary artery bypass graft
0.9% sodium chloride injection during on pump during Coronary artery bypass graft
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06378021