RecruitingPhase 3NCT06378021

Role of Calcium Chloride Injection in Alleviating Atrial Fibrillation Post CABG

Post Operative Atrial Fibrillation: Alleviation by Calcium Chloride Injection Into Cardiac Ganglionic Plexus During Coronary Artery Bypass Grafting.

Sponsor

Helwan University

Enrollment

100 participants

Start Date

Mar 14, 2024

Study Type

INTERVENTIONAL

Conditions

Atrial Fibrillation

Summary

This study hypothesize that injecting calcium chloride (CaCl2) into the major atrial ganglionated plexus (GPs) during on pump Coronary artery bypass graft (CABG) can reduce the incidence of Post operative Atrial fibrillation in the first 7 days after surgery.The study is designed to be prospective interventional study two armed RCT for on pump CABG patient. The intervention arm will be injected with Calcium chloride in the four major atrial ganglionic plexus The control arm will be injected with sodium chloride to determine the effect of Calcium chloride on Post CABG Atrial fibrillation

Eligibility

Min Age: 18 YearsMax Age: 74 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether giving calcium chloride (a mineral supplement) during open-heart bypass surgery (CABG) reduces the risk of developing atrial fibrillation (an irregular heartbeat) after the operation. **You may be eligible if...** - You are over 18 and under 75 years old - You are scheduled to undergo on-pump coronary artery bypass grafting (CABG) surgery **You may NOT be eligible if...** - You are over 75 years old - You already have atrial fibrillation before surgery - You have significant valve disease - Your heart's pumping function (ejection fraction) is below 30% - You are having a combined heart procedure (bypass plus another surgery) - You have a congenital heart defect, severe liver or kidney dysfunction, or poorly controlled overactive thyroid - You are having off-pump bypass surgery - You decline to participate Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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