the Predictive Value of Immune Cell in Locally Advanced Cervical Cancer

This study looks at how certain immune cells in the blood and tumor tissue can predict how well treatment will work for women with locally advanced cervical cancer. Researchers will track immune cell levels before and during treatment to see if they can be used as markers of response. **You may be eligible if...** - You are between 18 and 75 years old - You have been newly diagnosed with locally advanced cervical cancer (not yet treated) - Your cancer has been confirmed by a tissue test (biopsy) - Your blood counts, kidney function, and liver function are within acceptable ranges - You are physically well enough to receive chemotherapy and radiation together - Your doctor expects you to live at least 6 more months **You may NOT be eligible if...** - Your cancer has come back or spread to distant parts of the body - You have had another cancer in the past 5 years (excluding certain skin cancers) - You have an active autoimmune disease or are on long-term steroids - You have active hepatitis B or C - You have had an organ transplant or have HIV - You received a live vaccine in the past 30 days Talk to your doctor to see if this trial is right for you.