RecruitingNCT06380842

Organ Dysfunction Change in Acute Necrotizing Pancreatitis Patients With Sepsis After Open Necrosectomy

Organ Dysfunction Change in Acute Necrotizing Pancreatitis Patients With Sepsis Undergoing Open Necrosectomy


Sponsor

Chunling Jiang

Enrollment

200 participants

Start Date

Jun 15, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to characterize organ dysfunction change in acute necrotizing pancreatitis patients with sepsis after open necrosectomy.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Patients 18 years or older
  • Diagnosis of Acute pancreatitis according to the revised Atlanta classification, requires two of the following three criteria: (A) typical abdominal pain, (B) an increase in serum amylase or lipase levels higher than three times the upper limit of normality, and (C) signs of AP in imaging
  • Patients with confirmed or suspected infected pancreatic or peripancreatic necrosis were scheduled for open necrosectomy
  • Meet Sepsis-3 criteria

Exclusion Criteria2

  • Patients refuse to participate
  • Patients undergo repeat surgery on the same site

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Interventions

OTHERNecrotizing Pancreatitis patients' organ dysfunction progression

Study the dynamic nature of organ dysfunction


Locations(1)

West China Hospital, Sichuan University

Chengdu, China, China

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NCT06380842