Haplo-cord HCT vs. Haplo-HCT for T-ALL Patients

This study compares two types of stem cell transplants for patients with T-cell acute lymphoblastic leukemia (T-ALL): a haplo-cord transplant (using a half-matched donor plus cord blood) versus a standard half-matched (haploidentical) transplant alone. The goal is to see which approach leads to better outcomes. **You may be eligible if...** - You have T-cell acute lymphoblastic leukemia (a type of blood cancer) - Your disease can be tracked by sensitive tests (MRD testing) - You have a half-matched (haploidentical) donor available - You are willing to undergo a stem cell transplant - You are in reasonably good health (ECOG 0-3) **You may NOT be eligible if...** - You have another active cancer - A suitable cord blood unit cannot be found (for the haplo-cord group) - You have already had a stem cell transplant or CAR-T cell therapy - You have an uncontrolled infection Talk to your doctor to see if this trial is right for you.