RecruitingNCT06382740

Selection Protocol for Liver Transplantation in Patients Aged Over 70 Years

Prospective Evaluation of a Selection Protocol for Patients Over 70 Years Old for Liver Transplantation


Sponsor

Azienda Ospedaliera di Padova

Enrollment

18 participants

Start Date

Oct 1, 2022

Study Type

OBSERVATIONAL

Summary

Increased life expectancy and aging population has led to a trend of increasing liver transplant (LT) volume in the elderly. Nowadays, advanced age is not considered an absolute contraindication for LT but elderly LT candidates typically have an age-associated burden of comorbid conditions that can pose several clinical challenges during the selection/evaluation process for LT. Specific algorithms for elderly patient selection for LT are not well established; however, consensus agreement is that elderly LT candidates need a more rigorous selection process. This study proposes a "step by step" algorithm of selection for liver transplant candidates more than 70 years.


Eligibility

Min Age: 71 YearsMax Age: 75 Years

Inclusion Criteria4

  • Age >70 years and ≤ 75 years
  • Liver transplant from cadaveric donor
  • First liver transplant
  • End stage liver disease or liver tumor

Exclusion Criteria4

  • Age ≤ 70 years
  • Living donor liver transplant
  • Previous liver transplant
  • Liver transplant for acute liver failure

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Interventions

PROCEDURELiver transplantation

Liver transplantation


Locations(1)

U.O.C Chirurgia Epatobiliare e Trapianti Epatici, Azienda Ospedaliera di Padova

Padova, Italy

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NCT06382740