RecruitingNCT06382896

Effect of Oliceridine on Rebound Pain

A Clinical Study on the Effect of Oliceridine（TRV130） on Postoperative Rebound Pain and Early Rehabilitation Exercise After Knee Arthroscopy

Sponsor

The First Affiliated Hospital of Xiamen University

Enrollment

320 participants

Start Date

Jan 1, 2024

Study Type

OBSERVATIONAL

Conditions

Rebound Pain Arthroscopic Knee Surgery Oliceridine

Summary

The purpose of this clinical study was to identify the risk factors for postoperative pain outburst in patients undergoing arthroscopic knee surgery after Oliceridine and nerve block, and to evaluate the effect of oxeridine on early rehabilitation exercise in patients. A total of 320 patients undergoing arthroscopic knee arthroscopy under general anesthesia combined with femoral nerve block were selected to record the time and duration of postoperative pain outbreak, pain degree, age, gender, operation type, previous surgical history and other related risk factors.

Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria1

\. Age 18-70 years old;2. Body mass index (BMI) 18-30kg /m2;3. American Society of Anesthesiologists (ASA) Grade I to II;4. Hospital stay \>24h.

Exclusion Criteria1

\. Patients who cannot understand the numerical rating scale score and give feedback;2. Known allergy to the drug in the study;3. Infection of puncture site with nerve block;4. Oral analgesics for more than 2 weeks before surgery;5. Long-term use of glucocorticoids;6. Simultaneous surgery on both limbs;7. A psychopath;8. Severe compound trauma;9. Pregnant and lactating women.

Print for Your Doctor

Interested in this trial?

Get notified about updates and connect with the research team.