RecruitingNCT06388967
Pancreatic Cancer Detection Consortium
Early Detection of Pancreatic Cancer: Prospective Study
Sponsor
City of Hope Medical Center
Enrollment
2,000 participants
Start Date
Mar 15, 2023
Study Type
OBSERVATIONAL
Conditions
Pancreatic CancerPancreatic CarcinomaPancreatic Ductal AdenocarcinomaPancreatic AdenocarcinomaPancreatic NeoplasmsPancreatic Cancer, AdultPancreatic Cancer ResectablePancreatic Cancer Non-resectablePancreatic Cancer Stage IPancreatic Cancer StagePancreatic Cancer Stage 0Pancreatic Cancer Stage IIPancreatic Cancer Stage III
Summary
This study aims to prospective validate an exosome-based miRNA signature for noninvasive and early detection of pancreatic ductal adenocarcinoma.
Eligibility
Min Age: 18 Years
Inclusion Criteria3
- Histological diagnosis of pancreatic ductal adenocarcinoma, stages I-IV (TNM classification, 8th edition)
- Received standard diagnostic and staging procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment.
- Imaging- or endoscopy-based proof of lack of pancreatic ductal adenocarcinoma at the time of sampling (Non-disease controls)
Exclusion Criteria1
- Lack of written informed consent.
Interventions
DIAGNOSTIC_TESTPANcreatic cancer Exosome Early detectiON (PANXEON)
This test will utilize quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) to quantify the expression levels of 5 cell-free and 8 exosome-miRNAs in plasma samples obtained from patients with pancreatic ductal adenocarcinoma and from individuals without it
Locations(11)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06388967
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