Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy (INSITE)

This study tests new approaches — better imaging techniques and urine biomarker tests — to more accurately identify patients with muscle-invasive bladder cancer before surgery, ensuring they get the right operation (bladder removal vs. less aggressive procedures). **You may be eligible if...** - You have been diagnosed with bladder cancer and are being considered for surgical treatment - You are scheduled for a TURBT (a procedure to examine and remove bladder tumors) - You are at least 18 years old **You may NOT be eligible if...** - You have already had a definitive cystectomy (bladder removal) - You have metastatic bladder cancer - You are unable to undergo the required imaging or urine tests Talk to your doctor to see if this trial is right for you.