RecruitingNCT06399302

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes: PROMISE-Lung Study


Sponsor

Duke University

Enrollment

2,600 participants

Start Date

Sep 3, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This project aims to collect detailed clinical data, blood samples, and patient-reported outcomes from 2,600 lung transplant candidates, donors, and recipients at Lung Transplant Centers. The goal is to create a robust resource for various research objectives, including studying the impact of variations in donor and medical practices on clinical outcomes. The project also seeks to identify serum biomarkers associated with or predictive of specific post-transplant complications and conditions.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Able to understand and provide informed consent
  • ≥ 18 years of age at the time of written informed consent
  • Anticipated listing or listed for a single or bilateral cadaveric donor lung transplant or having received a lung transplant within 30 days

Exclusion Criteria3

  • Unwillingness of a participant or legally authorized representative (LAR) to give written informed consent or comply with study protocol
  • Pregnancy or plans to become pregnant
  • Past or current medical problems or findings from physical examination or laboratory testing, which, in the opinion of the investigator, may pose additional risks from participation in the study, may interfere with the participant's ability to comply with study requirements or that may impact the quality or interpretation of the data obtained from the study.

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Locations(17)

University of California Los Angeles

Los Angeles, California, United States

University of California at San Francisco

San Francisco, California, United States

University of Miami

Miami, Florida, United States

Johns Hopkins University

Baltimore, Maryland, United States

Brigham and Womens Hospital

Boston, Massachusetts, United States

University of Michigan

Ann Arbor, Michigan, United States

University of Minnesota

Minneapolis, Minnesota, United States

New York University

New York, New York, United States

Columbia University

New York, New York, United States

Duke University Medical Center

Durham, North Carolina, United States

University of Pennsylvania

Philadelphia, Pennsylvania, United States

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States

Vanderbilt University Medical Center

Nashville, Tennessee, United States

Inova Fairfax Hospital

Falls Church, Virginia, United States

University of Washington

Seattle, Washington, United States

University of Wisconsin Hospital and Clinics

Madison, Wisconsin, United States

University Health Network

Toronto, Canada

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NCT06399302


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