Topical Application of PRF Before Radiation Therapy

This study examines whether applying Platelet-Rich Fibrin (PRF) — a healing substance made from your own blood — to tooth extraction sites can reduce complications before radiation therapy in head and neck cancer patients. Radiation can cause serious jaw problems, so researchers are looking for ways to protect healing. **You may be eligible if...** - You have head or neck cancer and are about to receive radiation therapy - You need to have two teeth removed (bilateral extraction) before radiation begins - You are 18 years of age or older - Your tooth extractions can be done simply, without needing to cut the gum **You may NOT be eligible if...** - You have had previous radiation therapy to the head or neck - You are currently taking or have taken bisphosphonate medications (drugs for osteoporosis or bone metastases) - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.