RecruitingPhase 2NCT06408116

Predicting Esophageal Cancer Borders Using PET-Imaging

Predicting Esophageal Cancer Borders Using PET-Imaging PEGASUS


Sponsor

University Hospital Heidelberg

Enrollment

30 participants

Start Date

Mar 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The study examines the diagnostic precision of endosonography, mpMRI and PET/CT in defining tumor boundaries and tumor spread before and after neoadjuvant therapy and definitive surgery.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study examines whether a special type of PET scan using FAPI imaging can more precisely map the borders of esophageal cancer before surgery. Knowing exactly where a tumor ends could help surgeons remove it more completely. **You may be eligible if...** - You are 18 or older - You have been diagnosed with esophageal cancer (adenocarcinoma or squamous cell carcinoma) confirmed by biopsy - Surgery is planned as part of your treatment - You are in good general health (ECOG 0 or 1) **You may NOT be eligible if...** - You have had prior radiation therapy in the tumor area - You had another cancer diagnosis within the past 5 years - Surgery is not possible for medical or technical reasons - Your cancer has already spread to distant organs Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONphoton

radiation with 4-5 cm safte margin

PROCEDUREsurgical therapy

surgery based on PET-CT/MRI staging

DRUGChemotherapy

neoadjuvant chemotherapy


Locations(1)

Department of Radiotherapy, University of Heidelberg

Heidelberg, Germany

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NCT06408116


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